Firefighters attend the fire in Grafton Street, London.

Photograph: John Fahey/PA

One hundred firefighters are tackling a large blaze at a five-storey house in Mayfair, central London.

Twenty fire engines were called to Grafton Street, one of the city's most prestigious addresses, at around 5.30am.

Large parts of the terraced property's upper floors were alight, as well as the roof, said a spokeswoman for London fire brigade.

There were no reports of injuries and it is believed that residents in the house escaped before fire crews arrived.

The London fire commissioner, Ron Dobson, said: "Over 100 firefighters from fire stations across London are now working tirelessly to bring the serious fire in Mayfair under control.

"Steady progress is being made and as soon as the fire has been brought under control our fire investigators will be looking to establish how it started."

It is thought that surrounding roads, including Grafton Street, Albermarle Street, Dover Street and the top end of Bond Street are closed. Some local businesses have been temporarily shut.

The fire is the second major incident in central London overnight. A Kentucky Fried Chicken restaurant in a six-storey building in Leicester Square was largely destroyed by a fire at around 5am, Dobson said.